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Review
. 2018 Aug 8;99(3):430-433.
doi: 10.1016/j.neuron.2018.07.042.

The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System

Marc Hammarlund  1 , Oliver Hobert  2 , David M Miller 3rd  3 , Nenad Sestan  4
Affiliations
Review

The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System

Marc Hammarlund et al. Neuron. .

Abstract

Differential gene expression defines individual neuron types and determines how each contributes to circuit physiology and responds to injury and disease. The C. elegans Neuronal Gene Expression Map & Network (CeNGEN) will establish a comprehensive gene expression atlas of an entire nervous system at single-neuron resolution.

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Figures

Figure 1.
Figure 1.. Labeling Individual Neuron Classes
(A) The nervous system of the C. elegans hermaphrodite. From openworm.org. (B) Strategies to isolate individual neuron classes. In the intersectional strategies, transgenic lines expressing distinct GFP (green) and RFP (red) reporter transgenes are crossed together.
See this image and copyright information in PMC

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