The origin of device failure in fully encapsulated perovskite-based solar water splitting devices remains poorly understood. Here, the authors report an operando catalytic activity modulation strategy utilizing a photothermal catalyst with NIR laser toggling to monitor charge accumulation dynamics.

Efficient Kr/Xe separation is crucial for high-tech industries, defense, and aerospace applications. While conventional adsorbents typically capture Xe, their application is hindered by high energy costs during desorption. Here authors present a MOF with synergistic structural dynamics and local flexibility that reverses conventional selectivity, enabling preferential adsorption of Kr at room temperature.

Photocatalytic water splitting using a single particulate photocatalyst is a cost-efficient approach for sustainable hydrogen production. Here, the authors report a nanoscale Ba_xSr_1-xTaO₂N solid-solution photocatalyst exhibits an apparent quantum efficiency of 13.5% for H₂ evolution at 420 nm.

Energy gaps can be induced by spatial modulation of the electronic potential. Here, the authors demonstrate a large and robust energy gap in a free-standing carbon nanotube utilizing a 15-gate keyboard that spatially modulates the local potential.

Although having potentially useful applications, development of organogels that absorb nonpolar liquids is challenging. Here, the authors report the development of organogels with a nanowire-polymer networks, capable of absorbing and gelating nonpolar organic liquids.

Climate action could avoid over 1 million deaths globally from air pollution in 2040. However, it is suggested that cooperation is needed between developed and developing nations to ensure that disparities in air pollution are not perpetuated in the future.

A M5 earthquake triggered the 2018 Sierra Negra eruption after 10 hours. Subsequent microseismicity revealed a cryptic fluid phase facilitated magma intrusion, highlighting that cascading processes are potentially essential for eruption initiations.

Machine learning is used to understand emissions of the potent greenhouse gas nitrous oxide from the Southern Ocean. Low-pressure storms are found to drive emissions, leading to a revised picture of marine greenhouse gas cycling

China’s shale gas value chain can achieve net-negative carbon emissions through geological sequestration, offering a viable pathway for large-scale decarbonization in the energy sector.

This study quantifies Brazil’s soil carbon debt (1.40 Pg C) and demonstrates that improved agricultural practices enhance carbon recovery. The findings reveal Brazil’s significant capacity to mitigate emissions and influence global carbon markets.

Purinergic signalling dysregulation can drive inflammatory disorders, but effective targeted therapy is still lacking. Here, authors develop a smart DNA origami nanodevice that can precisely sense and metabolize high levels of extracellular ATP, thereby fine-tuning purinergic signalling and immune homeostasis.

Genome evolutionary history of wild Arachis species remains unclear. Here, the authors report the origin of small chromosome A08 and genome evolution of Arachis species via comparative oligopainting and genomic analysis of A. hoehnei.

SARS-CoV-2 variants often exhibit immune evasion, necessitating antiviral strategies beyond vaccination. This study presents a papain-like protease (PLpro) inhibitor called YL1004, which exhibits potent, broad-spectrum antiviral activity against wild-type, Delta, and Omicron variants in vitro and in vivo.

Experimental evolution enables evaluation of the relative roles of chance and necessity in evolution. This study compiles transcriptomic data from experimental evolution of a prokaryotic and five eukaryotic species in 22 environments to reveal that gene expression evolution is often repeatable and deterministic.

This study reports NIR probes targeting amyloid-β aggregates and cholinesterases for dual diagnostics and therapy. Lead probe I-43 detects Aβ in APP-PS1 mice, improves memory in a scopolamine model, and offers a template for future probe development.

People living with multiple long-term conditions often experience reduced quality of life, but evidence from Southeast Asia is fragmented. Here the authors show that commonly used tools indicate moderately reduced yet generally good quality of life, highlighting the need for context-sensitive measurement approaches.

Granzyme B is an important factor in cytotoxic T lymphocytes anti-tumour immunity. Here, the authors report on a Pd-FTn granzyme B-mimicking nanozyme with a binuclear catalytic centre, delivered by functionalised nanovesicles to selectively trigger caspase-dependent apoptosis for a T cell-inspired cancer therapy.

The PCRCR complex of Plasmodium spp. binds basigin on the erythrocyte surface. While Rh5 of the complex is restricted to P. falciparum, PTRAMP, CSS and Ripr orthologs are present across the genus, for which the authors report common features.

Preclinical studies indicate a synergistic effect of radiotherapy treatment (RT) and Immune checkpoint inhibitors (ICI) on tumor growth and metastasis. However, little is known about the immunomodulatory performance of different radioisotopes on the tumor microenvironment. Here, the authors employ alpha- versus beta-particle emitting radiopharmaceuticals in combination with dual ICI therapy and dissect mechanisms of in vivo immunomodulation and timing of ICI administration relative to RT, by comparing responses in immunogenic and non-immunogenic preclinical mouse models.

The molecular heterogeneity of brain metastases (BrMs) poses challenges for their treatment. Here, the authors generate a multi-omic, single cell, and spatially resolved atlas of 1,032 pan-cancer BrMs and identify four molecular subtypes with distinct biological and clinical features.

China’s shale gas value chain can achieve net-negative carbon emissions through geological sequestration, offering a viable pathway for large-scale decarbonization in the energy sector.

Humans conceptualize emotions using a two-dimensional affective space. Here, the authors show that hippocampal-prefrontal systems contain a map-like representation of emotion concepts that includes multiple levels of abstraction.

Feeding a growing population while protecting the environment is a major global challenge. This study suggests that agricultural diversification enhances long-term profitability, biodiversity, soil health, and climate benefits while maintaining crop yields, supporting a shift toward nature-positive farming.

Using interviews, this paper establishes that experts agree government intervention is critical in enabling climate-resilient housing, given the transformative potential of regulatory reform, finance, and information services.

European regions with the highest life expectancy, located in central and northern Spain, northern Italy, and Switzerland, continue to push the boundaries of human longevity, suggesting that there is still room for further lifespan extension.