January 9, 2020

VUMC Limited Submission Opportunity: 2020 Dalton Family Foundation Research Program in Appendix Cancer; deadline is Jan. 13

Applications due January 13

VUMC:  These instructions are for VUMC investigators. VU investigators should address any questions to VU-LSO@vanderbilt.edu.

VUMC seeks to select up to two candidates for funding by the 2020 Dalton Family Foundation Research Program in Appendix Cancer. The mission of this Request for Proposals is to promote investigation into the biology, biochemistry, genetics, pharmacology, and immunology of malignant cancers of the appendix of all types, which may lead to advances in diagnosis and treatment of this disease. High risk/high reward initiatives are preferred.

Proposals are requested in, but not limited to, the following areas:

  1. Development of new model systems including cell lines, organoids, or patient derived xenograft systems of appendix cancers that may be used for advancing investigation of the disease.
  2. Examination of the genetics and epigenetics of appendix cancers.
  3. Studies of the tumor microenvironment, immunobiology or metastatic determinants of appendix cancers.
  4. Development of diagnostic or therapeutic agents for appendix cancer.
  5. Studies of biological, diagnostic or therapeutic differences among different types of appendix tumors, or between appendix cancers and colon cancers.
  6. Clinical trials for diagnostic or therapeutic agents for appendix cancer.

Applicants can request a total of $50,000 - $200,000 over two years. Funding may be used to partially support the salary of research personnel involved and supplies related to the project. Budgets will include VUMC’s indirect costs, equal to 15% of the project’s total costs. The total budget request, inclusive of indirect costs, may not exceed $200,000. (For example, a total budget request of $200,000 would include $170,000 direct costs and $30,000 indirect costs.) It may be possible to apply for renewal with additional funding on subsequent RFP rounds.

Eligibility

  • PI must be a full-time faculty member with an appointment of Assistant Professor or higher at VUMC.
  • An application must have a single Principal Investigator for contact purposes.
  • Multidisciplinary projects with collaboration among VUMC investigators are encouraged.
  • VU faculty may serve as co-PIs and Investigators. VU faculty may not serve as PI.

Internal Application Process

Anyone interested in being considered as one of VUMC’s nominee must submit the following (in PDF format) to LSO@vanderbilt.edu by 5 p.m. on January 13, 2020.

  1. Brief (2 page maximum) research plan including summary budget. Please include name and affiliation of any collaborators.
  2. Statement of support from department chair/center director.
  3. NIH Biosketch.

Submissions should reference the program name in the subject line of the email.

After review by the internal selection committee, the chosen nominee(s) will submit a full proposal to the Foundation by the February 10, 2020 deadline.

Please contact us at LSO@vanderbilt.edu if you have any questions about the program, foundation, or internal review process.